·Genomic confirmation of hybridisation and recent inbreeding in a vector ‐ isolated Leishmania population.
PLoS genetics 2014;10;1;e1004092
PUBMED: 24453988
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·Vitamin B₁₂‐dependent taurine synthesis regulates growth and bone mass.
The Journal of clinical investigation 2014;124;7;2988‐3002
PUBMED: 24911144
·A comparison of key aspects of gene regulation in Streptomyces coelicolor and Escherichia coli using nucleotide‐resolution transcription maps produced in parallel by global and differential RNA sequencing.
Molecular microbiology 2014
PUBMED: 25266672
·Allele‐specific regulation of DISC1 expression by miR‐135b‐5p.
European journal of human genetics : EJHG 2014;22;6;840‐3
PUBMED: 24169524
·Genetic background drives transcriptional variation in human induced pluripotent stem cells.
PLoS genetics 2014;10;6;e1004432
PUBMED: 24901476
·Rapid conversion of EUCOMM/KOMP‐CSD alleles in mouse embryos using a cell‐permeable Cre recombinase.
Transgenic research 2014;23;1;177‐85
PUBMED: 24197666
·Deconstructing pheromone‐mediated behavior one layer at a time.
BMC biology 2014;12;1;33
PUBMED: 24884538
·Redundant mechanisms to form silent chromatin at pericentromeric regions rely on BEND3 and DNA methylation.
Molecular cell 2014;56;4;580‐94
PUBMED: 25457167
·Sequence of a Complete Chicken BG Haplotype Shows Dynamic Expansion and Contraction of Two Gene Lineages with Particular Expression Patterns.
PLoS genetics 2014;10;6;e1004417
PUBMED: 24901252
·Disruption of the potassium channel regulatory subunit KCNE2 causes iron‐deficient anemia.
Experimental hematology 2014;42;12;1053‐8.e1
PUBMED: 25127743
·The food‐borne identity.
Nature reviews. Microbiology 2014
PUBMED: 24975320
·Reagent and laboratory contamination can critically impact sequence‐based microbiome analyses.
BMC biology 2014;12;87
PUBMED: 25387460
·A framework for the interpretation of de novo mutation in human disease.
Nature genetics 2014
PUBMED: 25086666
·Potential of human induced pluripotent stem cells in studies of liver disease.
Hepatology (
PUBMED: 25502113
·Population and single cell genomics reveal the Aire‐dependency, relief from Polycomb silencing and distribution of self‐antigen expression in thymic epithelia.
Genome research 2014
PUBMED: 25224068
·Impact of infectious diseases consultation on the management of Staphylococcus aureus bacteraemia in children.
BMJ open 2014;4;7;e004659
PUBMED: 24989617
·The Yersinia pseudotuberculosis complex: characterization and delineation of a new species, Yersinia wautersii.
International journal of medical microbiology : IJMM 2014;304;3‐4;452‐63
PUBMED: 24598372
·A next‐generation dual‐recombinase system for time‐ and host‐specific targeting of pancreatic cancer.
Nature medicine 2014
PUBMED: 25326799
·Inferring human population size and separation history from multiple genome sequences.
Nature genetics 2014;46;8;919‐25
PUBMED: 24952747
·TreeFam v9: a new website, more species and orthology‐on‐the‐fly.
Nucleic acids research 2014;42;1;D922‐5
PUBMED: 24194607
·Single Cell Genomics meeting in Stockholm : from single cells to cell types.
Genome biology 2014;15;10;496
PUBMED: 25418892
·Common genetic variants highlight the role of insulin resistance and body fat distribution in type 2 diabetes, independently of obesity.
Diabetes 2014
PUBMED: 24947364
·Whole‐exome sequencing of patients with severe disorders of insulin action
Frontiers in Diabetes 2014;23;87‐101
DOI: 10.1159/000362469
·Re‐sequencing Expands Our Understanding of the Phenotypic Impact of Variants at GWAS Loci.
PLoS genetics 2014;10;1;e1004147
PUBMED: 24497850
·Genomic epidemiology of Vibrio cholerae O1 associated with floods, Pakistan , 2010.
Emerging infectious diseases 2014;20;1;13‐20
PUBMED: 24378019
·Genetic determinants of glucose‐6‐phosphate dehydrogenase activity in Kenya.
BMC medical genetics 2014;15;1;93
PUBMED: 25201310
·Hypothalamic control of bone metabolism.
Best practice & research. Clinical endocrinology & metabolism 2014;28;5;713‐23
PUBMED: 25256766
·Efficient genome modification by CRISPR‐Cas9 nickase with minimal off‐target effects.
Nature methods 2014;11;4;399‐402
PUBMED: 24584192
·Cryptic ecology among host generalist Campylobacter jejuni in domestic animals.
Molecular ecology 2014;23;10;2442‐51
PUBMED: 24689900
·Structural genomics analysis of uncharacterized protein families overrepresented in human gut bacteria identifies a novel glycoside hydrolase.
BMC bioinformatics 2014;15;1;112
PUBMED: 24742328
·An atlas of genetic influences on human blood metabolites.
Nature genetics 2014;46;6;543‐50
PUBMED: 24816252
·Plasmid deficiency in urogenital isolates of Chlamydia trachomatis reduces infectivity and virulence in a mouse model.
Pathogens and disease 2014;70;1;61‐9
PUBMED: 24022847
·Dissecting mammalian immunity through mutation.
Immunology and cell biology 2014
PUBMED: 24518983
·Genetic interaction implicates iRhom2 in the regulation of EGF receptor signalling in mice.
Biology open 2014
PUBMED: 25395669
·European surveillance network for influenza in pigs: surveillance programs, diagnostic tools and Swine influenza virus subtypes identified in 14 European countries from 2010 to 2013.
PloS one 2014;9;12;e115815
PUBMED: 25542013
·A cascade of DNA‐binding proteins for sexual commitment and development in Plasmodium.
Nature 2014;507;7491;253‐7
PUBMED: 24572359
·Comparative analysis of pseudogenes across three phyla.
Proceedings of the National Academy of Sciences of the United States of America 2014;111;37;13361‐6
PUBMED: 25157146
·Luminal Microbes Promote Monocyte‐Stem Cell Interactions Across a Healthy Colonic Epithelium.
Journal of immunology (Baltimore, Md. : 1950) 2014
PUBMED: 24907348
·Single‐cell genome‐wide bisulfite sequencing for assessing epigenetic heterogeneity.
Nature methods 2014;11;8;817‐20
PUBMED: 25042786
·Walking the interactome for candidate prioritization in exome sequencing studies of Mendelian diseases.
Bioinformatics (Oxford, England) 2014;30;22;3215‐22
PUBMED: 25078397
·Use of animal models for exome prioritization of rare disease genes.
Orphanet journal of rare diseases 2014;9;1;836
PUBMED: 25777709
·IFITM proteins‐cellular inhibitors of viral entry.
Current opinion in virology 2014;4;71‐7
PUBMED: 24480526
·DrsG from Streptococcus dysgalactiae subsp. equisimilis Inhibits the Antimicrobial Peptide LL‐37.
Infection and immunity 2014;82;6;2337‐44
PUBMED: 24664506
·Investigating the Feasibility of Scale up and Automation of Human Induced Pluripotent Stem Cells Cultured in Aggregates in Feeder Free Conditions.
Journal of biotechnology 2014
PUBMED: 24440272
·International Coordination of Large‐Scale Human Induced Pluripotent Stem Cell Initiatives: Wellcome Trust and ISSCR Workshops White Paper.
Stem cell reports 2014;3;6;931‐9
PUBMED: 25496616
·Secreted proteomes of different developmental stages of the gastrointestinal nematode Nippostrongylus brasiliensis.
Molecular & cellular proteomics : MCP 2014;13;10;2736‐51
PUBMED: 24994561
·A genome‐wide association study and biological pathway analysis of epilepsy prognosis in a prospective cohort of newly treated epilepsy.
Human molecular genetics 2014;23;1;247‐58
PUBMED: 23962720
·Neutrophils recruited by IL‐22 in peripheral tissues function as TRAIL‐dependent antiviral effectors against MCMV.
Cell host & microbe 2014;15;4;471‐83
PUBMED: 24721575
·Development of an antigen microarray for high throughput monoclonal antibody selection.
Biochemical and biophysical research communications 2014;445;4;785‐90
PUBMED: 24472540
·Common variant at 16p11.2 conferring risk of psychosis.
Molecular psychiatry 2014;19;1;108‐14
PUBMED: 23164818
·Comparative genome analysis of Wolbachia strain wAu.
BMC genomics 2014;15;928
PUBMED: 25341639
·Zero tolerance for healthcare‐associated MRSA bacteraemia: is it realistic?
The Journal of antimicrobial chemotherapy 2014;69;8;2238‐45
PUBMED: 24788657
·Resetting transcription factor control circuitry toward ground‐state pluripotency in human.
Cell 2014;158;6;1254‐69
PUBMED: 25215486
·Random projection based clustering for population genomics
Proceedings ‐ 2014 IEEE International Conference on Big Data, IEEE Big Data 2014 2014;675‐82
DOI: 10.1109/BigData.2014.7004291
·Investigating the possible causal association of smoking with depression and anxiety using Mendelian randomisation meta‐analysis: the CARTA consortium.
BMJ open 2014;4;10;e006141
PUBMED: 25293386
·Stratification by Smoking Status Reveals an Association of CHRNA5‐A3‐B4 Genotype with Body Mass Index in Never Smokers.
PLoS genetics 2014;10;12;e1004799
PUBMED: 25474695
·Clinical and pharmacogenomic implications of genetic variation in a Southern Ethiopian population.
The pharmacogenomics journal 2014
PUBMED: 25069476
·Differential PfEMP1 expression is associated with cerebral malaria pathology.
PLoS pathogens 2014;10;12;e1004537
PUBMED: 25473835
·Loss‐of‐function mutations in APOC3, triglycerides, and coronary disease.
The New England journal of medicine 2014;371;1;22‐31
PUBMED: 24941081
·Inactivating Mutations in NPC1L1 and Protection from Coronary Heart Disease.
The New England journal of medicine 2014
PUBMED: 25390462
·Typhoid fever in Fiji: a reversible plague?
Tropical medicine & international health : TM & IH 2014
PUBMED: 25066005
·Genetic background of extreme violent behavior.
Molecular psychiatry 2014
PUBMED: 25349169
·A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans.
Nature communications 2014;5;4871
PUBMED: 25225788
·Faster average case low memory semi‐external construction of the burrows‐wheeler transform
CEUR Workshop Proceedings 2014;1146;61‐68
URL: http://ceur-ws.org/Vol-1146/I…eedings.pdf
·Simulation and estimation of gene number in a biological pathway using almost complete saturation mutagenesis screening of haploid mouse cells.
BMC genomics 2014;15;1;1016
PUBMED: 25418962
·Complete Genome Sequences of Two Citrobacter rodentium Bacteriophages, CR8 and CR44b.
Genome announcements 2014;2;3
PUBMED: 24874665
·New mini‐ zincin structures provide a minimal scaffold for members of this metallopeptidase superfamily.
BMC bioinformatics 2014;15;1;1
PUBMED: 24383880
·Naturally Acquired Antibodies Specific for Plasmodium falciparum Reticulocyte‐Binding Protein Homologue 5 Inhibit Parasite Growth and Predict Protection From Malaria.
The Journal of infectious diseases 2014;209;5;789‐98
PUBMED: 24133188
·Summarizing specific profiles in Illumina sequencing from whole‐genome amplified DNA.
DNA research : an international journal for rapid publication of reports on genes and genomes 2014;21;3;243‐54
PUBMED: 24353264
·Cellular reprogramming by transcription factor engineering.
Current opinion in genetics & development 2014;28C;1‐9
PUBMED: 25151337
·Cigarette smoking reduces DNA methylation levels at multiple genomic loci but the effect is partially reversible upon cessation.
Epigenetics : official journal of the DNA Methylation Society 2014;9;10;1382‐96
PUBMED: 25424692
·Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes.
Science (New York, N.Y.) 2014;345;6196;1251343
PUBMED: 25082706
·Chromosome x‐wide association study identifies Loci for fasting insulin and height and evidence for incomplete dosage compensation.
PLoS genetics 2014;10;2;e1004127
PUBMED: 24516404
·Human genetics: pre‐Columbian Pacific contact.
Current biology : CB 2014;24;21;R1038‐40
PUBMED: 25517365
·Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum.
Nature communications 2014;5;5521
PUBMED: 25422853
·Heps with pep: direct reprogramming into human hepatocytes.
Cell stem cell 2014;14;3;267‐9
PUBMED: 24607399
·Harmonization of Neuroticism and Extraversion phenotypes across inventories and cohorts in the Genetics of Personality Consortium: an application of Item Response Theory.
Behavior genetics 2014
PUBMED: 24828478
·TMEM129 is a Derlin‐1 associated ERAD E3 ligase essential for virus‐induced degradation of MHC‐I.
Proceedings of the National Academy of Sciences of the United States of America 2014
PUBMED: 25030448
·Cancer gene discovery goes mobile.
Nature genetics 2014;46;9;928‐9
PUBMED: 25162801
·In vivo evolution of antimicrobial resistance in a series of Staphylococcus aureus patient isolates: the entire picture or a cautionary tale?
The Journal of antimicrobial chemotherapy 2014;69;2;363‐7
PUBMED: 24047554
·Common genetic variants do not associate with CAD in familial hypercholesterolemia.
European journal of human genetics : EJHG 2014;22;6;809‐13
PUBMED: 24219970
·The Challenges of Genome‐Wide Interaction Studies: Lessons to Learn from the Analysis of HDL Blood Levels.
PloS one 2014;9;10;e109290
PUBMED: 25329471
·Single cell analysis of cancer genomes.
Current opinion in genetics & development 2014;24C;82‐91
PUBMED: 24531336
·The classical lancefield antigen of group a Streptococcus is a virulence determinant with implications for vaccine design.
Cell host & microbe 2014;15;6;729‐40
PUBMED: 24922575
·Defining the estimated core genome of bacterial populations using a bayesian decision model.
PLoS computational biology 2014;10;8;e1003788
PUBMED: 25144616
·Genetic determinants of long‐term changes in blood lipid concentrations: 10‐year follow‐up of the GLACIER study.
PLoS genetics 2014;10;6;e1004388
PUBMED: 24922540
·RNA‐seq analysis of the influence of anaerobiosis and FNR on Shigella flexneri.
BMC genomics 2014;15;438
PUBMED: 24907032
·Genetic diversity in Puerto Rico and its implications for the peopling of the Island and the West Indies.
American journal of physical anthropology 2014;155;3;352‐68
PUBMED: 25043798
·Detecting and measuring selection from gene frequency data.
Genetics 2014;196;3;799‐817
PUBMED: 24361938
·Identification of enterotoxigenic Escherichia coli (ETEC) clades with long‐term global distribution.
Nature genetics 2014;46;12;1321‐6
PUBMED: 25383970
·Metabolic signatures of adiposity in young adults: Mendelian randomization analysis and effects of weight change.
PLoS medicine 2014;11;12;e1001765
PUBMED: 25490400
·An outpatient, ambulant‐design, controlled human infection model using escalating doses of salmonella typhi challenge delivered in sodium bicarbonate solution.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2014;58;9;1230‐40
PUBMED: 24519873
·Whole Exome Re‐Sequencing Implicates CCDC38 and Cilia Structure and Function in Resistance to Smoking Related Airflow Obstruction.
PLoS genetics 2014;10;5;e1004314
PUBMED: 24786987
·Adding genomic ‘foliage’ to the tree of life.
Nature reviews. Microbiology 2014;12;2;78
PUBMED: 24429416
·The genetic basis of plasmid tropism between Chlamydia trachomatis and Chlamydia muridarum.
Pathogens and disease 2014;72;1;19‐23
PUBMED: 24700815
·Voyage to the bottom of the ‘seaquence’.
Nature reviews. Microbiology 2014;12;9;597
PUBMED: 25118883
·Contemporary gene flow between wild An. gambiae s.s. and An. arabiensis.
Parasites & vectors 2014;7;345
PUBMED: 25060488
·Next‐generation pathogen genomics.
Genome biology 2014;15;11;528
PUBMED: 25417942
·The OMSSAPercolator: an automated tool to validate OMSSA results.
Proteomics 2014;14;9;1011‐4
PUBMED: 24504981
·A genome wide association study of Plasmodium falciparum susceptibility to 22 antimalarial drugs in Kenya.
PloS one 2014;9;5;e96486
PUBMED: 24809681
·Phenotyping structural abnormalities in mouse embryos using high‐resolution episcopic microscopy.
Disease models & mechanisms 2014;7;10;1143‐52
PUBMED: 25256713
·A risk‐based approach to reducing exposure of staff to laboratory animal allergens.
Lab animal 2014;44;1;32‐8
PUBMED: 25526057
·A membrane topology model for human interferon inducible transmembrane protein 1.
PloS one 2014;9;8;e104341
PUBMED: 25105503
·Selective nuclear export of specific classes of mRNA from mammalian nuclei is promoted by GANP.
Nucleic acids research 2014;42;8;5059‐71
PUBMED: 24510098
·Single‐cell analyses of regulatory network perturbations using enhancer‐targeting TALEs suggest novel roles for PU.1 during haematopoietic specification.
Development (Cambridge, England) 2014;141;20;4018‐30
PUBMED: 25252941
·Heterozygous Loss‐of‐Function Mutations in YAP1 Cause Both Isolated and Syndromic Optic Fissure Closure Defects.
American journal of human genetics 2014;94;2;295‐302
PUBMED: 24462371
·Integrating non‐coding RNAs in JAK‐STAT regulatory networks.
JAK‐STAT 2014;3;1;e28055
PUBMED: 24778925
·Epigenome‐wide DNA methylation in hearing ability: new mechanisms for an old problem.
PloS one 2014;9;9;e105729
PUBMED: 25184702
·Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo.
Cancer cell 2014;25;6;794‐808
PUBMED: 24835589
·Inactivating CUX1 mutations promote tumorigenesis.
Nature genetics 2014;46;1;33‐8
PUBMED: 24316979
·Defining the role of common variation in the genomic and biological architecture of adult human height.
Nature genetics 2014
PUBMED: 25282103
·Plasmodium falciparum Erythrocyte Invasion: Combining Function with Immune Evasion.
PLoS pathogens 2014;10;3;e1003943
PUBMED: 24651270
·Conceptual issues for screening in the genomic era ‐ time for an update?
Epidemiology Biostatistics and Public Health 2014;11;4;1‐8
DOI: 10.2427/9944
·Rolled‐up Functionalized Nanomembranes as Three‐Dimensional Cavities for Single Cell Studies.
Nano letters 2014;14;8;4197‐204
PUBMED: 24598026
·NetworkAnalyst ‐ integrative approaches for protein‐protein interaction network analysis and visual exploration.
Nucleic acids research 2014;42;Web Server issue;W167‐74
PUBMED: 24861621
·Estimating genome‐wide significance for whole‐genome sequencing studies.
Genetic epidemiology 2014;38;4;281‐90
PUBMED: 24676807
·PredictProtein‐an open resource for online prediction of protein structural and functional features.
Nucleic acids research 2014;42;Web Server issue;W337‐43
PUBMED: 24799431
·The association between circulating lipoprotein(a) and type 2 diabetes: is it causal?
Diabetes 2014;63;1;332‐42
PUBMED: 24089516
·Response to Comment on Ye et al. The Association Between Circulating Lipoprotein(a) and Type 2 Diabetes: Is It Causal? Diabetes 2014;63:332‐342.
Diabetes 2014;63;8;e15
PUBMED: 25060897
·Estimation of Epistatic Variance Components and Heritability in Founder Populations and Crosses.
Genetics 2014
PUBMED: 25326236
·Long term conservation of human metabolic phenotypes and link to heritability.
Metabolomics : Official journal of the Metabolomic Society 2014;10;5;1005‐1017
PUBMED: 25177233
·A comparative encyclopedia of DNA elements in the mouse genome.
Nature 2014;515;7527;355‐64
PUBMED: 25409824
·A genome‐wide assessment of the role of untagged copy number variants in type 1 diabetes.
PLoS genetics 2014;10;5;e1004367
PUBMED: 24875393
·The AURORA initiative for metastatic breast cancer.
British journal of cancer 2014
PUBMED: 25225904
·Repeated landmass reformation limits diversification in the widespread littoral zone mosquito Anopheles sundaicus sensu lato in the Indo‐Oriental Region.
Molecular ecology 2014;23;10;2573‐89
PUBMED: 24750501
·Using genetically isolated populations to understand the genomic basis of disease.
Genome medicine 2014;6;10;83
PUBMED: 25473423
·Effective diagnosis of genetic disease by computational phenotype analysis of the disease‐associated genome.
Science translational medicine 2014;6;252;252ra123
PUBMED: 25186178
·Towards a comprehensive Plasmodium falciparum merozoite cell surface and secreted recombinant protein library.
Malaria journal 2014;13;93
PUBMED: 24620899
·Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing.
Science (New York, N.Y.) 2014;346;6206;256‐9
PUBMED: 25301631
·One‐step generation of different immunodeficient mice with multiple gene modifications by CRISPR/Cas9 mediated genome engineering.
The international journal of biochemistry & cell biology 2014;46;49‐55
PUBMED: 24269190
·Transient Darwinian selection in Salmonella enterica serovar Paratyphi A during 450 years of global spread of enteric fever.
Proceedings of the National Academy of Sciences of the United States of America 2014;111;33;12199‐204
PUBMED: 25092320











